Maganti Lab

A multi-disciplinary approach to understand Hematopoietic Stem Cell biology

Publications

Discover a selection of pivotal publications authored by various members of Maganti lab with contribution from other labs, which underpin the research endeavors of our lab. These works reflect the rigorous scientific inquiry and collaborative ethos propelling our advancements in stem cell research and its therapeutic applications. Each entry below is a testament to the knowledge and expertise anchoring our lab’s mission.

Reduction in cord blood graft potency due to processing delay can be prevented by trehalose supplementation
Suria Jahan, Harinad B Maganti, Jaina Patel, Roya Pasha, Emily Doxtator, Javed K Manesia, Nicolas Pineault
Vox Sang. 2025 May;120(5):490-502
doi: 10.1111/vox.70012; PMID: 40132801
Robust Expansion of Hematopoietic Stem Cells Ex Vivo Using Small Molecule Cocktails
https://link.springer.com/protocol/10.1007/7651_2024_582
Woratree Kaewsakulthong, Ajay Ratan Pasala, Justine Hanotaux, Tanvir Hasan, Harinad B Maganti
Methods Mol Biol. 2024 Nov 26.
 doi: 10.1007/7651_2024_582; PMID: 39587002
Impact of lower concentrations of dimethyl sulfoxide on cryopreservation of autologous hematopoietic stem cells: a systematic review and meta-analysis of controlled clinical studies
https://www.isct-cytotherapy.org/article/S1465-3249(24)00053-7/abstract
Bryenah Bennett*, Justine Hanotaux*, Ajay Ratan Pasala, Tanvir Hasan, Dhuha Hassan, Risa Shor, David S Allan, Harinad B Maganti
*Co-first authors
Cytotherapy. 2024 Feb 21:S1465-3249(24)00053-7.
 doi: 10.1016/j.jcyt.2024.02.006; PMID: 38416086
Homing and Engraftment of Hematopoietic Stem Cells Following Transplantation: A Pre-Clinical Perspective
https://www.mdpi.com/1718-7729/31/2/44
Tanvir Hasan*, Ajay Ratan Pasala*, Dhuha Hassan, Justine Hanotaux, David S. Allan, Harinad B. Maganti
*Co-first authors
Curr. Oncol. 2024, 31(2), 603-616; https://doi.org/10.3390/curroncol31020044 (registering DOI)
AA2P-mediated DNA demethylation synergizes with stem cell agonists to promote expansion of hematopoietic stem cells
https://www.cell.com/cell-reports-methods/fulltext/S2667-2375(23)00340-5
https://pubmed.ncbi.nlm.nih.gov/38070507/
Javed K Manesia*, Harinad B Maganti*, Sakhar Almoflehi, Suria Jahan, Tanvir Hasan, Roya Pasha, Chelsea McGregor, Nellie Dumont, Josée Laganière, Julie Audet, Nicolas Pineault
*Co-first authors
Cell Reports Methods. December 08, 2023. DOI:https://doi.org/10.1016/j.crmeth.2023.100663 PMID: 38070507
Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies https://pubmed.ncbi.nlm.nih.gov/35039239/
Harinad B Maganti, Aidan M Kirkham, Adrian J M Bailey, Risa Shorr, Natasha Kekre, Nicolas Pineault, David S Allan
Cytotherapy. 2022 Apr;24(4):405-412. doi: 10.1016/j.jcyt.2021.10.010. Epub 2022 Jan 14. PMID: 35039239
Persistence of CRISPR/Cas9 gene edited hematopoietic stem cells following transplantation: A systematic review and meta-analysis of preclinical studies
https://pubmed.ncbi.nlm.nih.gov/33666363/
Harinad B Maganti, Adrian J M Bailey, Aidan M Kirkham, Risa Shorr, Nicolas Pineault, David S Allan
Stem Cells Transl Med. 2021 Jul;10(7):996-1007. doi: 10.1002/sctm.20-0520. Epub 2021 Mar 5. PMID: 33666363; PMCID: PMC8235122
Clinical Outcomes of Umbilical Cord Blood Transplantation Using Ex Vivo Expansion: A Systematic Review and Meta-Analysis of Controlled Studies
https://pubmed.ncbi.nlm.nih.gov/36396108/
Tana Saiyin, Aidan M Kirkham, Adrian J M Bailey, Risa Shorr, Nicolas Pineault, Harinad B Maganti, David S Allan
Transplant Cell Ther. 2023 Feb;29(2):129.e1-129.e9. doi: 10.1016/j.jtct.2022.11.007. Epub 2022 Nov 15. PMID: 36396108
Targeting the MTF2-MDM2 Axis Sensitizes Refractory Acute Myeloid Leukemia to Chemotherapy
https://pubmed.ncbi.nlm.nih.gov/30115703/
Harinad B Maganti, Hani Jrade, Christopher Cafariello, Janet L Manias Rothberg, Christopher J Porter, Julien Yockell-Lelièvre, Hannah L Battaion, Safwat T Khan, Joel P Howard, Yuefeng Li, Adrian T Grzybowski, Elham Sabri, Alexander J Ruthenburg, F Jeffrey Dilworth, Theodore J Perkins, Mitchell Sabloff, Caryn Y Ito, William L Stanford
Cancer Discov. 2018 Nov;8(11):1376-1389. doi: 10.1158/2159-8290.CD-17-0841. Epub 2018 Aug 16. PMID: 30115703; PMCID: PMC7200079
Mtf2-PRC2 control of canonical Wnt signaling is required for definitive erythropoiesis
https://pubmed.ncbi.nlm.nih.gov/29736258/
Janet L Manias Rothberg, Harinad B Maganti, Hani Jrade, Christopher J Porter, Gareth A Palidwor, Christopher Cafariello, Hannah L Battaion, Safwat T Khan, Theodore J Perkins, Robert F Paulson, Caryn Y Ito, William L Stanford
Cell Discov. 2018 May 1;4:21. doi: 10.1038/s41421-018-0022-5. PMID: 29736258; PMCID: PMC5928144